Vladislav Namestnikov and Nino Niederreiter each had a goal and an assist.
Dylan DeMelo also scored for the Jets.
Mason Appleton had three assists.
Connor Hellebuyck made 16 saves for Winnipeg, Nathan Walker scored twice and Jimmy Snuggerud found the net once for the Blues.
Jordan Binnington turned aside 21 shots for St. Louis, Kyle Connor scored 1:23 into the contest when Mark Scheifele fed him from behind the goal line into the slot and the Jet winger made no mistake, wiring a wrister past Binnington, beating him high glove side to make it 1-0.
The goal was his 4th of the playoffs.
Nathan Walker drew the Blues even at 3:42 when he tipped a Colton Parayko wrister through Connor Hellebuyck's legs to make it 1-1.
The goal was his 1st of the playoffs.
Nino Niederreiter tipped a Dylan Samberg shot from the point through traffic past Binnington at 8:39 to restore the Jet one goal lead.
The goal was his 1st of the playoffs.
Mark Scheifele left the game over the intermission and did not return to the game.
The Jets responded, scoring twice and outshooting the Blues 14-3 in the second period.
"I'm really proud of the effort," said Jets captain Adam Lowry, who also tallied into an empty net. "I think sometimes when you lose your number one centre you lose a key piece of your lineup. There can be a bit of a sag and emotional letdown. But you know I thought the guys really rallied around it. Coming into the intermission and then finding out he's (Scheifele) not coming back. Guys needed to step up."
Jimmy Snuggerud scored just over six minutes into the second period when Robert Thomas hit him with a cross ice feed after cruising over the Jets blueline.
The rookie winger beat Hellebuyck short side with a low wrister to score his second of the post-season.
The Jets took the lead just over the 11 minute mark when Dylan DeMelo's wrister from the right point hit St. Louis defenceman Colton Parayko and beat Binnington to make it 3-2.
The goal was his first of the playoffs.
Vladislav Namestnikov made it 4-2 after he converted a nifty relay pass from Kyle Connor and beat Binnington as he moved across the crease to give Winnipeg a two-goal cushion.
Adam Lowry added an empty netter with 3:13 left in regulation to make it 5-2 and seal the win for the Jets.
The goal was his 2nd of the playoffs.
Nathan Walker scored with 51 seconds left in regulation to make it 5-3.
St. Louis Blues Head Coach Jim Montgomery was succinct in his assessment on the game and the hit that took out Jets top player Mark Scheifele.
They were better than us," he said succinctly. "There's a lot of facets but we're onto the next one. Like it's a playoff series. I thought that was their (Jets) best game. I thought that was our worst game. We're onto the next one. We can analyze every part of it, they were better." "And let's make it clear. 55 got hurt from the Faksa hit. He played six minutes after the Schenn hit. He didn't come back after he got rocked by Faksa," added Montgomery.
Jets Head Coach Scott Arniel said Montgomery should have kept his thoughts on the hit to himself.
"Well I didn't know Monty (Montgomery) got his medical degree," quipped Arniel. "Trying to say how our player got hurt. He's way off base. He should not make that comment." Game 6 goes Friday in St. Louis.
SHOTS-ST. LOUIS 19 WINNIPEG 26
ATTENDANCE-15,225
