Ryan Reaves, John Tavares and Simon Benoit also scored for the Maple Leafs.
Morgan Reilly and Mitch Marner each had two assists for the Maple Leafs.
Ilya Samsonov made 24 saves for Toronto, who moved to 25-14-8.
Dylan Samberg and Mason Appleton scored for the Jets.
Connor Hellebuyck stopped 26 shots for Winnipeg, who dropped to 30-12-5.
Dylan Samberg gave the Jets an early lead 4:11 into the contest when he floated a wrister from the left point through traffic and past Samsonov to make it 1-0.
The goal was his 1st of the season and first in 77 games.
Ryan Reaves tied the game at 19:11 when he redirected Tyler Bertuzzi appeared to put Toronto ahead at 19:50 when he knocked the puck past Hellebuyck but Michael Nylander interfered with the Jet goaltender, shoving him back into the net.
The play was ruled no goal by the officials and upheld upon appeal.
There was no scoring in the second period.
John Tavares gave Toronto the lead on the power play just under two minutes into the third period.
With Dylan DeMelo off for tripping, the Leafs veteran tipped a Morgan Reilly shot past Hellebuyck to make it 2-1 at 1:54.
The goal was his 13th of the season.
Auston Matthews gave Toronto a cushion at the 15:28 mark of the third period with a power play goal after he blasted a Mitch Marnner feed from the slot past Hellebuyck to make it 3-1.
The goal was his 40th of the season.
Simon Benoit added an empty netter at 18:22 to seal the win for the Maple Leafs.
Mason Appleton scored with 11.8 seconds left in regulation for the Jets.
SHOTS-TORONTO 30 WINNIPEG 26
ATTENDANCE-15,225
